The magical preserve Fablehaven provides refuge to numerous mystical species: centaurs, trolls, satyrs, ogres, fairies, minotaurs, brownies, imps, nymphs, and many others. But some beings are too large and powerful to be confined to regular enchanted refuges. These mightiest of creatures dwell inside the dragon sanctuaries.

When Kendra and Seth go to stay at their grandparents' estate, they discover that it is a sanctuary for magical creatures and that a battle between good and evil is looming.